Marked hyperferritinemia does not predict for HLH in the adult population-Reference-Cited by-同舟云学术

Marked hyperferritinemia does not predict for HLH in the adult population

Published:2015-03-05 Issue:10 Volume:125 Page:1548-1552
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Schram Alison M.¹,Campigotto Federico²,Mullally Ann³,Fogerty Annemarie⁴,Massarotti Elena⁵,Neuberg Donna²,Berliner Nancy³^ORCID

Affiliation:

1. Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;

2. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA; and

3. Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA;

4. Division of Hematology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; and

5. Division of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

Abstract

Key Points Highly elevated ferritin is not specific for hemophagocytic lymphohistiocytosis in adults. Marked hyperferritinemia in adults most often occurs in the setting of renal failure, hepatocellular injury, infection, or malignancy.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/10/1548/1383089/1548.pdf

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4. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.;Henter;Pediatr Blood Cancer,2007

5. Hemophagocytic syndromes—an update.;Janka;Blood Rev,2014

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