KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse-Reference-Cited by-同舟云学术

KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse

Published:2014-10-02 Issue:14 Volume:124 Page:2248-2251
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Babor Florian¹,Manser Angela R.²,Fischer Johannes C.²,Scherenschlich Nadine¹,Enczmann Jürgen²,Chazara Olympe³,Moffett Ashley³,Borkhardt Arndt¹,Meisel Roland¹,Uhrberg Markus²

Affiliation:

1. Department of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Heinrich Heine University, Düsseldorf, Germany;

2. Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany; and

3. Department of Pathology and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom

Abstract

Key Points C2 confers increased susceptibility to childhood B-ALL. C2 is associated with increased risk of late relapse in childhood B-ALL.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/14/2248/1379894/2248.pdf

Reference17 articles.

1. Homozygosity for human leucocyte antigen-C ligands of KIR2DL1 is associated with increased risk of relapse after human leucocyte antigen-C-matched unrelated donor haematopoietic stem cell transplantation.;Giebel;Br J Haematol,2005