Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics-Reference-Cited by-同舟云学术

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics

Published:2014-04-17 Issue:16 Volume:123 Page:e37-e45
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Simon Lukas M.¹²,Edelstein Leonard C.³,Nagalla Srikanth³,Woodley Angela B.⁴,Chen Edward S.²,Kong Xianguo³,Ma Lin³,Fortina Paolo⁵⁶,Kunapuli Satya⁷,Holinstat Michael³,McKenzie Steven E.³,Dong Jing-fei⁸,Shaw Chad A.²⁹,Bray Paul F.³

Affiliation:

1. Department of Structural and Computational Biology and Molecular Biophysics, and

2. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX;

3. The Cardeza Foundation for Hematologic Research and the Department of Medicine, Thomas Jefferson University, Philadelphia, PA;

4. Department of Medicine, Baylor College of Medicine, Houston, TX;

5. Cancer Genomics Laboratory, Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA;

6. Department of Molecular Medicine, Sapienza Universita’ di Roma, Rome, Italy;

7. Sol Sherry Thrombosis Center, Temple University, Philadelphia, PA;

8. Puget Sound Blood Center, Seattle, WA; and

9. Department of Statistics, Rice University, Houston, TX

Abstract

Key Points Unique dataset of human platelet mRNA, miRNA, and physiology reveals mRNAs and miRNAs that differ by age and gender. Interactive public web tool (www.plateletomics.com) provides biologic insights into platelet function and gene expression.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/16/e37/1376269/e37.pdf

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