β1 integrin−mediated signals are required for platelet granule secretion and hemostasis in mouse-Reference-Cited by-同舟云学术

β1 integrin−mediated signals are required for platelet granule secretion and hemostasis in mouse

Published:2013-10-10 Issue:15 Volume:122 Page:2723-2731
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Petzold Tobias¹²³,Ruppert Raphael¹,Pandey Dharmendra¹,Barocke Verena²,Meyer Hannelore¹,Lorenz Michael²³,Zhang Lin²³,Siess Wolfgang³⁴,Massberg Steffen²³,Moser Markus¹

Affiliation:

1. Department of Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany;

2. Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany;

3. Munich Heart Alliance, Munich, Germany; and

4. Institute for Prevention of Cardiovascular Diseases, Universität München, Munich, Germany

Abstract

Key Points Platelet β1 integrin−mediated signals control granule secretion and hemostasis β1 integrin−mediated outside-in signaling is independent of direct kindlin-integrin interaction

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/15/2723/1369614/2723.pdf

Reference30 articles.

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4. Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen.;Holtkötter;J Biol Chem,2002

5. Structural insights into the interactions between platelet receptors and fibrillar collagen.;Herr;J Biol Chem,2009

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