Horizontal RNA transfer mediates platelet-induced hepatocyte proliferation-Reference-Cited by-同舟云学术

Horizontal RNA transfer mediates platelet-induced hepatocyte proliferation

Published:2015-08-06 Issue:6 Volume:126 Page:798-806
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kirschbaum Marc¹,Karimian Golnar¹,Adelmeijer Jelle¹,Giepmans Ben N. G.²,Porte Robert J.³,Lisman Ton¹³

Affiliation:

1. Surgical Research Laboratory,

2. Department of Cell Biology, and

3. Section of Hepatobiliairy Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

Abstract

Key Points Platelets stimulate proliferation of HepG2 cells, which requires uptake of platelets by the HepG2 cell. Platelets stimulate HepG2 cell proliferation in part by transfer of RNA from the anucleate platelet to the nucleated HepG2 cell.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/6/798/1391170/798.pdf

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