GATA-3 promotes T-cell specification by repressing B-cell potential in pro–T cells in mice-Reference-Cited by-同舟云学术

GATA-3 promotes T-cell specification by repressing B-cell potential in pro–T cells in mice

Published:2013-03-07 Issue:10 Volume:121 Page:1749-1759
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

García-Ojeda Marcos E.¹²³,Klein Wolterink Roel G. J.¹²⁴⁵,Lemaître Fabrice²⁶,Richard-Le Goff Odile¹²,Hasan Milena¹²⁷,Hendriks Rudolf W.⁴,Cumano Ana²³,Di Santo James P.¹²

Affiliation:

1. Innate Immunity Unit, Institut Pasteur, Paris, France;

2. Inserm U668, Paris, France;

3. Lymphocyte Development Unit, Institut Pasteur, Paris, France;

4. Department of Pulmonary Medicine, Erasmus MC Rotterdam, Rotterdam, The Netherlands;

5. University Paris Diderot, Sorbonne Paris Cité, Cellule Pasteur, Paris, France; and

6. Immune Response Dynamics Unit,

7. Center for Human Immunology, Institut Pasteur, Paris, France

Abstract

Key Points Gata3 is critical for the transition of “double-negative” (DN) thymocyte DN1 to DN2. Gata3 represses a latent B-cell potential in DN thymocytes.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/10/1749/1363546/1749.pdf

Reference50 articles.

1. Molecular genetics of T cell development.;Rothenberg;Annu Rev Immunol,2005

2. Untangling the T branch of the hematopoiesis tree.;Chi;Curr Opin Immunol,2009

3. Delta-like 4 is indispensable in thymic environment specific for T cell development.;Hozumi;J Exp Med,2008

4. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.;Koch;J Exp Med,2008

5. Notch1 expression in early lymphopoiesis influences B versus T lineage determination.;Pui;Immunity,1999

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