SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury-Reference-Cited by-同舟云学术

SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

Published:2014-07-10 Issue:2 Volume:124 Page:277-286
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Niswander Lisa M.¹²,Fegan Katherine H.¹,Kingsley Paul D.¹,McGrath Kathleen E.¹,Palis James¹^ORCID

Affiliation:

1. Center for Pediatric Biomedical Research, Department of Pediatrics, and

2. Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY

Abstract

Key Points SDF-1 acutely affects megakaryocyte spatial distribution in the bone marrow at steady state and in the setting of radiation injury. SDF-1-directed localization of megakaryocytes into the vascular niche increases platelet output.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/2/277/1381323/277.pdf

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