Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria-Reference-Cited by-同舟云学术

Glycosylphosphatidylinositol-specific, CD1d-restricted T cells in paroxysmal nocturnal hemoglobinuria

Published:2013-04-04 Issue:14 Volume:121 Page:2753-2761
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Gargiulo Lucia¹²,Papaioannou Maria¹,Sica Michela²,Talini Giulia²,Chaidos Aristeidis¹,Richichi Barbara³,Nikolaev Andrei V.⁴,Nativi Cristina³,Layton Mark¹,de la Fuente Josu⁵,Roberts Irene¹,Luzzatto Lucio⁶,Notaro Rosario²,Karadimitris Anastasios¹

Affiliation:

1. Centre for Haematology, Department of Medicine, Hammersmith Hospital, Imperial College London, London, United Kingdom;

2. Cancer Genetics and Gene Transfer-Core Research Laboratory, Istituto Toscano Tumori, Firenze, Italy;

3. Dipartimento di Chimica, Università di Firenze, Sesto Fiorentino, Italy;

4. Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom;

5. Paediatric Haematology, Blood and Marrow Transplant Programme, St. Mary’s Hospital, Imperial College Healthcare National Health Service (NHS) Trust, London, United Kingdom; and

6. Istituto Toscano Tumori, Firenze, Italy

Abstract

Key Points The mechanism of bone marrow failure (BMF) in PNH is not known. Novel CD1d-restricted, GPI-specific T cells are present in PNH patients and might be responsible for BMF.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/14/2753/1365203/2753.pdf

Reference39 articles.

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3. Biosynthesis, remodelling and functions of mammalian GPI-anchored proteins: recent progress.;Kinoshita;J Biochem,2008

4. Diagnosis and management of paroxysmal nocturnal hemoglobinuria.;Parker;Blood,2005

5. Natural history of paroxysmal nocturnal hemoglobinuria.;Hillmen;N Engl J Med,1995

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