Late mortality after autologous blood or marrow transplantation in childhood: a Blood or Marrow Transplant Survivor Study-2 report

Author:

Holmqvist Anna Sällfors12,Chen Yanjun3,Wu Jessica3,Battles Kevin3,Bhatia Ravi4,Francisco Liton3,Hageman Lindsey3,Kung Michelle3,Ness Emily3,Parman Mariel3,Salzman Donna4,Winther Jeanette Falck56,Rosenthal Joseph7,Forman Stephen J.7,Weisdorf Daniel J.8,Arora Mukta8,Armenian Saro H.7,Bhatia Smita3

Affiliation:

1. Pediatric Oncology and Hematology, Skåne University Hospital, Lund, Sweden;

2. Department of Clinical Sciences, Lund University, Lund, Sweden;

3. Institute for Cancer Outcomes and Survivorship and

4. Division of Hematology, Oncology and Bone Marrow Transplantation, University of Alabama at Birmingham, Birmingham, AL;

5. Danish Cancer Society Research Center, Copenhagen, Denmark;

6. Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark;

7. Pediatric Hematology/Oncology, City of Hope, Duarte, CA; and

8. Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN

Abstract

Key Points Two-year survivors of autologous BMT in childhood have a substantially increased risk of late mortality compared with the general population. There has been a significant decline in all-cause mortality in children undergoing autologous BMT over the past 3 decades.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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