Long-term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL: updated results of the CLL8 trial

Author:

Fischer Kirsten1,Bahlo Jasmin1,Fink Anna Maria1,Goede Valentin1,Herling Carmen Diana1,Cramer Paula1,Langerbeins Petra1,von Tresckow Julia1,Engelke Anja1,Maurer Christian1,Kovacs Gabor1,Herling Marco1,Tausch Eugen2,Kreuzer Karl-Anton1,Eichhorst Barbara1,Böttcher Sebastian3,Seymour John F.4,Ghia Paolo5,Marlton Paula67,Kneba Michael3,Wendtner Clemens-Martin18,Döhner Hartmut2,Stilgenbauer Stephan2,Hallek Michael19

Affiliation:

1. Department I for Internal Medicine and Center of Integrated Oncology, University of Cologne, Cologne, Germany;

2. Department of Internal Medicine III, University of Ulm, Ulm, Germany;

3. Department of Internal Medicine II, University Hospital of Schleswig-Holstein, Kiel, Germany;

4. Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia;

5. Division of Experimental Oncology and Department of Onco-Hematology, Università Vita-Salute San Raffaele and Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Scientifico San Raffaele, Milano, Italy;

6. Princess Alexandra Hospital, Brisbane, Australia;

7. University of Queensland, Brisbane, Australia;

8. Department of Hematology, Oncology, Immunology, Palliative Care, Infectious Diseases and Tropical Medicine, Klinikum Schwabing, Munich, Germany; and

9. Cluster of Excellence Cellular Stress Responses in Aging Associated Diseases, University of Cologne, Cologne, Germany

Abstract

Key Points Long-term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL. Updated results on safety and efficacy of the CLL8 trial.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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