1. Department of Internal Medicine II, University Würzburg, Würzburg, Germany;
2. Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany;
3. Center of Internal Medicine, Goethe University Frankfurt, Frankfurt, Germany;
4. Amgen Research (Munich) GmbH, Munich, Germany;
5. Medical Department II, University Hospital Schleswig-Holstein, Kiel, Germany;
6. Medical Department III, University Ulm, Ulm, Germany;
7. Medical Department A, University Münster, Münster, Germany;
8. Medical Department, Carl Gustav Carus University, Dresden, Germany;
9. Metronomia GmbH, Munich, Germany;
10. Department for Hematology and Oncology and Tumor Immunology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany;
11. Department of Immunology University Munich, Munich, Germany; and
12. Onkologikum, Frankfurt, Germany