Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin–specific clinical impact-Reference-Cited by-同舟云学术

Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin–specific clinical impact

Published:2017-05-18 Issue:20 Volume:129 Page:2760-2770
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Ennishi Daisuke¹,Mottok Anja¹,Ben-Neriah Susana¹,Shulha Hennady P.¹,Farinha Pedro¹,Chan Fong Chun¹,Meissner Barbara¹,Boyle Merrill¹,Hother Christoffer¹,Kridel Robert¹,Lai Daniel²,Saberi Saeed²,Bashashati Ali²,Shah Sohrab P.²,Morin Ryan D.³,Marra Marco A.³,Savage Kerry J.¹,Sehn Laurie H.¹,Steidl Christian¹,Connors Joseph M.¹,Gascoyne Randy D.¹,Scott David W.¹

Affiliation:

1. Centre for Lymphoid Cancer,

2. Molecular Oncology, and

3. Genome Science Centre, British Columbia Cancer Agency, Vancouver, BC, Canada

Abstract

Key Points MYC and BCL2 genetic alterations are associated with COO subtype-specific clinical effect in R-CHOP-treated DLBCL.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/20/2760/1400615/blood747022.pdf

Reference50 articles.

1. MYC on the path to cancer;Dang;Cell,2012

2. Reflecting on 25 years with MYC;Meyer;Nat Rev Cancer,2008

3. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells;Vaux;Nature,1988

4. Understanding MYC-driven aggressive B-cell lymphomas: pathogenesis and classification;Ott;Blood,2013

5. The t(14;18) is associated with germinal center-derived diffuse large B-cell lymphoma and is a strong predictor of outcome;Barrans;Clin Cancer Res,2003

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