Resting and activated endothelial cells are increased in the peripheral blood of cancer patients-Reference-Cited by-同舟云学术

Resting and activated endothelial cells are increased in the peripheral blood of cancer patients

Published:2001-06-01 Issue:11 Volume:97 Page:3658-3661
ISSN:1528-0020
Container-title:Blood
language:en
Short-container-title:

Author:

Mancuso Patrizia¹,Burlini Alessandra¹,Pruneri Giancarlo¹,Goldhirsch Aron¹,Martinelli Giovanni¹,Bertolini Francesco¹

Affiliation:

1. From the Divisions of Hematology-Oncology, Pathology-Laboratory Medicine, and Medical Oncology, European Institute of Oncology, Milan, Italy.

Abstract

Circulating endothelial cells (CECs) were enumerated in 20 healthy controls and 76 newly diagnosed cancer patients by means of 4-color flow cytometry. In breast cancer (n = 46) and lymphoma (n = 30) patients, both resting and activated CECs were increased by 5-fold (P < .0008 vs control). CECs significantly correlated with plasma levels of vascular cell adhesion molecule-1 and vascular endothelial growth factor. Resting and activated CECs were similar to healthy controls in 7 lymphoma patients achieving complete remission after chemotherapy, and activated CECs were found to decrease in 13 breast cancer patients evaluated before and 24 hours after quadrantectomy.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/97/11/3658/1674031/h8110103658.pdf

Reference20 articles.

1. Circulating endothelial cells in sickle cell anemia.;Solovey;N Engl J Med.,1997

2. Circulating cytomegalovirus-infected endothelial cells in patients with an active CMV infection.;Grefte;J Infect Dis.,1993

3. Diagnosis of Mediterranean spotted fever by indirect immunofluorescence of Rickettsia conorii in circulating endothelial cells isolated with monoclonal antibody-coated immunomagnetic beads.;Drancourt;J Infect Dis.,1992

4. Direct evidence of endothelial injury in acute myocardial infarction and unstable angina by demonstration of circulating endothelial cells.;Mutin;Blood.,1999

5. Origins of circulating endothelial cells and endothelial outgrowth from blood.;Lin;J Clin Invest.,2000

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