DiaNe: A New First-Level Computerized Tool Assessing Memory, Attention, and Visuospatial Processing to Detect Early Pathological Cognitive Decline

Author:

Di Vita Antonella1,Vecchione Francesca23,Boccia Maddalena23,Bocchi Alessia1,Cinelli Maria Cristina3,Mirino Pierandrea234,Teghil Alice23,D’Antonio Fabrizia1,de Lena Carlo5,Piccardi Laura23,Giannini Anna Maria2,Guariglia Cecilia23

Affiliation:

1. Department of Human Neurosciences, “Sapienza” University of Rome, Rome, Italy

2. Department of Psychology, “Sapienza” University of Rome, Rome, Italy

3. Cognitive and Motor Rehabilitation and Neuroimaging Unit, IRCCS Santa Lucia, Rome, Italy

4. PhD Program in Behavioral Neuroscience, “Sapienza” University of Rome, Rome, Italy

5. IRCCS San Raffaele Roma, Rome, Italy

Abstract

Background: Detecting the beginning of cognitive decay is crucial to guarantee good management and the possible prevention of dementia progression. The present study arises from observations collected during an educational event to promote mental and physical health in which incidental neuropsychological data gathered on 290 citizens showed the importance of routine neuropsychological examination in detecting early signs of cognitive decay, since many individuals were unaware of the decrease in their cognitive efficiency. Accordingly, the availability of a screening tool that is computerized, portable, self-administrable, and sensitive to the main neurocognitive changes testifying the progression towards pathological aging is critical. Objective: To this aim, we developed a computerized battery for the early, preclinical Diagnosis of Neurocognitive disease (DiaNe), that can be self-administered and performed autonomously by using a tablet. Methods: DiaNe includes tests expected to evaluate the main cognitive domains involved in neurodegenerative diseases (memory, attention, executive functions) with a detailed assessment of visuospatial memory in particular. Results: DiaNe is not just the translation of standard tests into telematics, rather it is a new tool that provides both accuracy and response time measurements, aimed to screen cognitive profile and monitor it over time, being able to detect changes in still normal performances that may be suggestive of an ongoing onset of neurocognitive disorders. Conclusion: Here we present an investigation of DiaNe concurrent validity showing that its results are comparable to those obtained by existing paper-and-pencil neuropsychological tests, and propose that DiaNe could be a useful, quick, and economical instrument for the monitoring of cognitive aging.

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference44 articles.

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