Effects of the Acetylcholine Release Agent ST101 with Donepezil in Alzheimer’s Disease: A Randomized Phase 2 Study
Author:
Affiliation:
1. McGill Centre for Studies in Aging (MCSA), McGill University, Montreal, QC, Canada
2. Department of Neurology, Baylor College of Medicine, Houston, TX, USA
3. Sonexa Therapeutics Inc., San Diego, CA, USA
Publisher
IOS Press
Subject
Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience
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3. A novel azaindolizinone derivative ZSET1446 (spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one) improves methamphetamine-induced impairment of recognition memory in mice by activating extracellular signal-regulated kinase 1/2;Ito;J Pharmacol Exp Ther,2007
4. Spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101) treatment rescues olfactory bulbectomy-induced memory impairment by activating Ca2+/calmodulin kinase II and protein kinase C in mouse hippocampus;Han;J Pharmacol Exp Ther,2008
5. A novel cognitive enhancer, ZSET1446/ST101, promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice;Shioda;J Pharmacol Exp Ther,2010
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