Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation

Author:

Leoutsakos Jeannie-Marie S.1,Yan Haijuan1,Anderson William S.2,Asaad Wael F.3,Baltuch Gordon4,Burke Anna5,Chakravarty M. Mallar6,Drake Kristen E.7,Foote Kelly D.8,Fosdick Lisa7,Giacobbe Peter9,Mari Zoltan10,McAndrews Mary Pat9,Munro Cynthia A.1,Oh Esther S.1,Okun Michael S.8,Pendergrass Jo Cara11,Ponce Francisco A.12,Rosenberg Paul B.1,Sabbagh Marwan N.13,Salloway Stephen14,Tang-Wai David F.915,Targum Steven D.7,Wolk David16,Lozano Andres M.9,Smith Gwenn S.1,Lyketsos Constantine G.1

Affiliation:

1. Department of Psychiatry and Behavioral Sciences, Memory and Alzheimer’s Treatment Center andAlzheimer’s Disease Research Center, Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA

2. Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA

3. Department of Neurosurgery, Rhode Island Hospital and the Alpert Medical School of Brown University, Providence, RI, USA

4. Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA

5. Banner Alzheimer’s Institute, Phoenix, AZ, USA | [m] Department of Neurology, University of Arizona College of Medicine, Phoenix, AZ, USA

6. Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, QC, Canada; Departments of Psychiatry and Biomedical Engineering, McGill University, Montreal, QC, Canada

7. Functional Neuromodulation Ltd, Minneapolis, MN, USA

8. Departments of Neurology and Neurosurgery, University of Florida Center for Movement Disorders and Neurorestoration, Gainesville, FL, USA

9. Departments of Medicine (Neurology), Surgery (Neurosurgery) Psychologyand Psychiatry, University of Toronto, Toronto, ON, Canada

10. Department of Neurology, NevadaMovement Disorders Program, Cleveland Clinic Lou Ruvo Center for Brain Health, University of Nevada, Las Vegas, NV, USA

11. Clintara LLC, Boston, MA, USA

12. Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ, USA

13. Alzheimer’s Disease and Memory Disorders Division, Barrow Neurological Institute, St. Joseph’sHospital and Medical Center, Phoenix, AZ, USA

14. Department of Neurology, Butler Hospital and theAlpert Medical School of Brown University, Providence, RI, USA

15. University Health NetworkMemory Clinic, University of Toronto, Division of Neurology, Toronto, ON, Canada

16. Department of Neurology, Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

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