Expression of the Alzheimer’s Disease Mutations AβPP695sw and PSEN1M146I in Double-Transgenic Göttingen Minipigs-Reference-Cited by-同舟云学术

Expression of the Alzheimer’s Disease Mutations AβPP695sw and PSEN1M146I in Double-Transgenic Göttingen Minipigs

Published:2016-08-08 Issue:4 Volume:53 Page:1617-1630
ISSN:1387-2877
Container-title:Journal of Alzheimer's Disease
language:
Short-container-title:JAD

Author:

Jakobsen Jannik E.¹,Johansen Marianne G.¹,Schmidt Mette²,Liu Ying³,Li Rong³,Callesen Henrik³,Melnikova Margarita⁴,Habekost Mette¹,Matrone Carmela¹,Bouter Yvonne⁵,Bayer Thomas A.⁵,Nielsen Anders Lade¹,Duthie Monika⁶,Fraser Paul E.⁶,Holm Ida E.⁷⁴,Jørgensen Arne Lund¹

Affiliation:

1. Department of Biomedicine (East), Aarhus University, Aarhus C, Denmark

2. Department of Large Animal Sciences/Reproduction, University of Copenhagen, Frederiksberg C, Denmark

3. Department of Animal Science, Aarhus University, Tjele, Denmark

4. Department of Pathology, Randers Hospital, Randers, Denmark

5. Division of Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University Medicine Göttingen, Georg-August-University Göttingen, Göttingen, Germany

6. Tanz Centre for Research in Neurodegenerative Diseases, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

7. Department of Clinical Medicine, Aarhus University, Aarhus C, Denmark

Publisher

IOS Press

Subject

Psychiatry and Mental health,Geriatrics and Gerontology,Clinical Psychology,General Medicine,General Neuroscience

Reference51 articles.

1. Genetically modified pigs to model human diseases;Flisikowska;J Appl Genet,2014

2. Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer;Rogers;J Clin Invest,2008

3. Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs;Rogers;Science,2008

4. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth;Stoltz;Sci Transl Med,2010

5. The DeltaF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs;Ostedgaard;Sci Transl Med,2011

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