Author:
Jiang Xia,Li Li,Xue Hong-Yuan
Abstract
BACKGROUND: In the past ten years, liver biopsies have been used as a method to accurately diagnose the stage of fibrosis. OBJECTIVE: This study aimed to evaluate whether body position and exercise affect the measurement of liver Young’s modulus of healthy volunteers by real-time shear wave elastography (RT-SWE). Methods: RT-SWE was used to measure liver Young’s modulus in the supine and left lateral positions of 70 healthy volunteers at rest and measure the liver Young’s modulus in the lying position before exercise, and at zero, five, and ten minutes of rest after exercise. RESULTS: The liver Young’s modulus in the left lateral position was significantly higher than in the supine position (P< 0.05), and the measured value in the supine position was more stable than the left lateral position. The liver Young’s modulus measured at zero minutes after exercise was significantly higher than that measured before exercise (P< 0.05). The liver Young’s modulus measured at five minutes after exercise was significantly higher than that measured at zero minutes after exercise (P<0.05) and was not statistically different from the measured value before exercise (P> 0.05). The liver Young’s modulus measured at ten minutes after exercise was significantly higher from that measured at zero minutes after exercise (P< 0.05) and was not statistically different from the measured value at five minutes after exercise (P> 0.05). CONCLUSION: Body position and exercise have a significant impact on the measurement of liver Young’s modulus. It is recommended that the examinees take a supine position during the measurement, and measurement should be conducted at least ten minutes after exercise.
Subject
Health Informatics,Biomedical Engineering,Information Systems,Biomaterials,Bioengineering,Biophysics
Reference35 articles.
1. Utilization rates, complications and costs of percutaneous liver biopsy: a population-based study including 4275 biopsies;Myers;Liver Int.,2008
2. Variability of grade and stage in simultaneous paired liver biopsies in patients with hepatitis C;Skripenova;J Clin Pathol.,2007
3. Shear wave spectroscopy for in vivo quantification of human soft tissues visco-elasticity;Deffieux;IEEE Trans Med Imaging.,2009
4. The application research of shear wave elastography (SWE) in the evaluation of chronic hepatitis B;Mu;Journal of Medical Imaging.,2017
5. C Y. The clinical value of real-time shear wave elastography in evaluating the degree of chronic liver fibrosis. China Medical Device Information. 2019; 7: 62-63.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献