1. Bristol Trials Centre, University of Bristol, Bristol, UK
2. Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
3. Department of Cardiology, Bristol Heart Institute, Bristol, UK
4. National Institute for Health Research Biomedical Research Centre, Department of Population Health Sciences, University of Bristol, Bristol, UK
5. National Institute for Health Research Applied Research Collaboration West (NIHR ARC West), Bristol, UK
6. Bristol Medical School, University of Bristol, Bristol, UK
7. Norwich Medical School, University of East Anglia, Norwich, UK
8. Institute of Applied Health Research, University of Birmingham, Birmingham, UK
9. Health and Social Sciences, University of the West of England, Bristol, Bristol, UK