Author:
Ueda Mitsuhiro,Uenoyama Yoshitaka,Terasoma Nozomi,Doi Shoko,Kobayashi Shoji,Ryu Ilhyong,Murphy John A
Abstract
A straightforward synthesis of 4,4-spirocyclic indol γ-lactams by tandem radical cyclization of iodoaryl allyl azides with CO was achieved. The reaction of iodoaryl allyl azides, TTMSS and AIBN under CO pressure (80 atm) in THF at 80 °C gave the desired 4,4-spirocyclic indoline, benzofuran, and oxindole γ-lactams in moderate to good yields.
Cited by
14 articles.
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