Use of an Automated Method Improves the Yield and Quality of Cell-Free Fetal DNA Extracted from Maternal Plasma
Author:
Affiliation:
1. University Women’s Hospital, Department of Research, Basel, Switzerland
2. Center for Research in Biomedicine, UWE Bristol Genomics, Research Institute, University of the West of England, Bristol, United Kingdom
Publisher
Oxford University Press (OUP)
Subject
Biochemistry, medical,Clinical Biochemistry
Link
http://academic.oup.com/clinchem/article-pdf/51/12/2419/32684556/clinchem2419.pdf
Reference7 articles.
1. Hahn S, Holzgreve W. Prenatal diagnosis using fetal cells and cell-free fetal DNA in maternal blood: what is currently feasible?. Clin Obstet Gynecol2002;45:649-656.
2. Chiu RW, Lo YM. The biology and diagnostic applications of fetal DNA and RNA in maternal plasma. Curr Top Dev Biol2004;61:81-111.
3. Lo YM, Tein MS, Lau TK, Haines CJ, Leung TN, Poon PM, et al. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am J Hum Genet1998;62:768-775.
4. Li Y, Zimmermann B, Rusterholz C, Kang A, Holzgreve W, Hahn S. Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms. Clin Chem2004;50:1002-1011.
5. Li Y, Di Naro E, Vitucci A, Zimmermann B, Holzgreve W, Hahn S. Detection of paternally inherited fetal point mutations for β-thalassemia using size-fractionated cell-free DNA in maternal plasma. JAMA2005;293:843-849.
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