Can Metabolic Profiles Be Used as a Phenotypic Readout of the Genome to Enhance Precision Medicine?
Author:
Affiliation:
1. Department of Genetics, Stanford University School of Medicine, Stanford, CA
Funder
NIH
Publisher
Oxford University Press (OUP)
Subject
Biochemistry, medical,Clinical Biochemistry
Link
http://academic.oup.com/clinchem/article-pdf/62/5/676/32644280/clinchem0676.pdf
Reference5 articles.
1. Optimized analytical procedures for the untargeted metabolomic profiling of human urine and plasma by combining hydrophilic interaction (HILIC) and reverse-phase liquid chromatography (RPLC)-mass spectrometry;Contrepois;Mol Cell Prot,2015
2. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum;Gieger;PLoS Genet,2008
3. Plasma metabolomic profiles enhance precision medicine for volunteers of normal health;Guo;Proc Nat Acad Sci USA,2015
4. Host-gut microbiota metabolic interactions;Nicholson;Science,2012
5. Personal omics profiling reveals dynamic molecular and medical phenotypes;Chen;Cell,2012
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