Umpolung cyclization reaction of N-cinnamoylthioureas in the presence of DBU-Reference-Cited by-同舟云学术

Umpolung cyclization reaction of N-cinnamoylthioureas in the presence of DBU

Published:2018 Issue:42 Volume:16 Page:7910-7919
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Saito Rei¹²³⁴⁵,Uemura Naohiro¹²³⁴⁵,Ishikawa Hiroki¹²³⁴⁵,Magara Akina¹²³⁴⁵,Yoshida Yasushi¹²³⁴⁵^ORCID,Mino Takashi¹²³⁴⁵^ORCID,Kasashima Yoshio⁶⁷⁸⁹¹⁰,Sakamoto Masami¹²³⁴⁵^ORCID

Affiliation:

1. Department of Applied Chemistry and Biotechnology

2. Graduate School of Engineering

3. Chiba University

4. Chiba

5. 263-8522 Japan

6. Education Center

7. Faculty of Creative Engineering

8. Chiba Institute of Technology

9. Chiba 275-0023

10. Japan

Abstract

The reaction of N-cinnamoylthioureas with DBU proceeded in an unprecedented “umpolung” cyclization fashion to give five-membered iminothiazolidinones and/or thiohydantoins.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB02066C

Reference50 articles.

1. Dual Targeting of Adenosine A2A Receptors and Monoamine Oxidase B by 4H-3,1-Benzothiazin-4-ones

2. Androgen Receptor Antagonists and Anti-Prostate Cancer Activities of Some Newly Synthesized Substituted Fused Pyrazolo-, Triazolo- and Thiazolo-Pyrimidine Derivatives

3. Synthesis and antimicrobial activity of novel 2-thiazolylimino-5-arylidene-4-thiazolidinones