Combined therapy of ruthenium dendrimers and anti-cancer drugs against human leukemic cells

Author:

Michlewska Sylwia12345ORCID,Maroto Marta6789,Hołota Marcin453,Kubczak Malgorzata453,Sanz del Olmo Natalia6789,Ortega Paula678910ORCID,Shcharbin Dzmitry111213ORCID,de la Mata Francisco Javier678910ORCID,Bryszewska Maria453ORCID,Ionov Maksim453ORCID

Affiliation:

1. Laboratory of Microscopic Imaging & Specialized Biological Techniques. Faculty of Biology & Environmental Protection. University of Lodz

2. Lodz 90-237

3. Poland

4. Department of General Biophysics. Faculty of Biology & Environmental Protection. University of Lodz

5. Lodz 90-236

6. Universidad de Alcalá. Department of Organic and Inorganic Chemistry

7. and Research Institute in Chemistry “Andrés M. del Río” (IQAR)

8. Madrid

9. Spain

10. Networking Research Center on Bioengineering

11. Institute of Biophysics & Cell Engineering of NASB

12. 220072 Minsk

13. Belarus

Abstract

A new family of cationic ruthenium(ii) metallodendrimers of a carbosilane nature with the metal centre coordinated to 2-aminopyridine ligands have been synthesized and interacted with conventional anticancer drugs.

Funder

Narodowa Agencja Wymiany Akademickiej

Narodowe Centrum Nauki

Instituto de Salud Carlos III

European Cooperation in Science and Technology

Ministerio de Economía y Competitividad

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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