One-pot facile synthesis of 4-amino-1,8-naphthalimide derived Tröger's bases via a nucleophilic displacement approach-Reference-Cited by-同舟云学术

One-pot facile synthesis of 4-amino-1,8-naphthalimide derived Tröger's bases via a nucleophilic displacement approach

Published:2017 Issue:35 Volume:15 Page:7321-7329
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Shanmugaraju Sankarasekaran¹²³⁴⁵,McAdams Deirdre¹²³⁴⁵,Pancotti Francesca¹²³⁴⁵,Hawes Chris S.¹²³⁴⁵^ORCID,Veale Emma B.¹²³⁴⁵,Kitchen Jonathan A.⁶⁷⁸⁹¹⁰,Gunnlaugsson Thorfinnur¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry and Trinity Biomedical Sciences Institute (TBSI)

2. Trinity College Dublin

3. The University of Dublin

4. Dublin 2

5. Ireland

6. Chemistry

7. Faculty of Natural and Environmental Sciences

8. University of Southampton-Highfield

9. Southampton

10. UK

Abstract

We report here a novel one-pot synthetic strategy for the synthesis of a family of N-alkyl-1,8-naphthalimide derived Tröger's bases (in overall yield of 65–96%) via a nucleophilic substitution reaction.

Funder

Irish Research Council

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01835E

Reference94 articles.

1. Ueber ?-Naphtoacridin. Vorl�ufige Mittheilung

2. Bowl-shaped Tröger's bases and their recognition properties