Self-assembly and intracellular delivery of DNA by a truncated fragment derived from theTrojanpeptidePenetratin-Reference-Cited by-同舟云学术

Self-assembly and intracellular delivery of DNA by a truncated fragment derived from theTrojanpeptidePenetratin

Published:2020 Issue:20 Volume:16 Page:4746-4755
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Mello Lucas R.¹²³^ORCID,Hamley Ian W.⁴⁵⁶⁷^ORCID,Castelletto Valeria⁴⁵⁶⁷,Garcia Bianca B. M.¹²³,Lourenço Thiago C.¹²³,Vassiliades Sandra V.⁸⁹¹⁰³,Alves Wendel A.⁸⁹¹⁰³^ORCID,Han Sang W.¹²³,Silva Emerson R.¹²³^ORCID

Affiliation:

1. Departamento de Biofísica

2. Universidade Federal de São Paulo

3. Brazil

4. Department of Chemistry

5. University of Reading

6. Reading RGD 6AD

7. UK

8. Centro de Ciências Naturais e Humanas

9. Universidade Federal do ABC

10. Santo André 09210-580

Abstract

A heptamer containing the longest noncationic amino acid sequence ofPenetratinis shown to form peptiplexes with DNA. The structure is characterized from molecular to nanoscopic scale and peptiplexes are shown to assist intracell delivery of DNA.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Engineering and Physical Sciences Research Council

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SM/D0SM00347F

Reference69 articles.