Synthesis and characterization of new fluorescent boro-β-carboline dyes-Reference-Cited by-同舟云学术

Synthesis and characterization of new fluorescent boro-β-carboline dyes

Published:2021 Issue:21 Volume:11 Page:12802-12807
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Szepesi Kovács Dénes¹²³⁴⁵,Hajdu Imre¹²³⁴⁵,Mészáros Gergely¹⁶³⁴⁷,Wittner Lucia¹⁶³⁴^ORCID,Meszéna Domokos¹⁶³⁴⁷^ORCID,Tóth Estilla Zsófia¹⁶³⁴⁸^ORCID,Hegedűs Zita⁹¹⁰¹¹⁴,Ranđelović Ivan⁹¹⁰¹¹⁴,Tóvári József⁹¹⁰¹¹⁴,Szabó Tímea¹²¹³¹⁴⁴^ORCID,Szilágyi Bence⁵¹⁵¹⁶⁴,Milen Mátyás¹²¹³¹⁴⁴^ORCID,Keserű György Miklós¹²³⁴⁵^ORCID,Ábrányi-Balogh Péter¹²³⁴⁵^ORCID

Affiliation:

1. Research Centre for Natural Sciences

2. Medicinal Chemistry Research Group

3. 1519 Budapest

4. Hungary

5. Department of Organic Chemistry and Technology

6. Comparative Psychophysiology Research Group

7. Faculty of Information Technology and Bionics

8. János Szentágothai Doctoral School of Neurosciences

9. National Institute of Oncology

10. Department of Experimental Pharmacology

11. 1525 Budapest

12. Egis Pharmaceuticals Plc.

13. Directorate of Drug Substance Development

14. 1475 Budapest

15. Budapest University of Technology and Economics

16. 1521 Budapest

Abstract

The first representatives of fluorescent boro-β-carbolines were applied for labeling trastuzumab. The antibody fluorophore conjugate was confirmed as a useful tool for labeling and imaging tumour cells in confocal and two-photon microscopy.

Funder

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA02132J

Reference26 articles.

1. Harnessing Natural Product Diversity for Fluorophore Discovery: Naturally Occurring Fluorescent Hydroxyanthraquinones from the Marine Crinoid Pterometra venusta

2. Fluorescent natural products as probes and tracers in biology

3. A Pyrimidine-β-carboline and Other Alkaloids from Annona foetida with Antileishmanial Activity