Concentric annular liquid–liquid phase separation for flow chemistry and continuous processing-Reference-Cited by-同舟云学术

Concentric annular liquid–liquid phase separation for flow chemistry and continuous processing

Published:2021 Issue:9 Volume:6 Page:1635-1643
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Harding Matthew J.¹²^ORCID,Feng Bin¹,Lopez-Rodriguez Rafael¹³,O'Connor Heather⁴,Dowling Denis⁴,Gibson Geoff⁵,Girard Kevin P.⁶^ORCID,Ferguson Steven¹²³⁷^ORCID

Affiliation:

1. School of Chemical and Bioprocess Engineering, University College Dublin, Belfield, Dublin 4, Ireland

2. I-form, the SFI Research Centre for Advanced Manufacturing, School of Chemical and Bioprocess Engineering, University College Dublin, Belfield, Dublin 4, Ireland

3. SSPC, the SFI Research Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Belfield, Dublin 4, Ireland

4. I-form, the SFI Research Centre for Advanced Manufacturing, School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, Ireland

5. Pfizer Inc. Global Supply, Ringaskiddy, Ireland

6. Chemical R&D, Pfizer Inc., Groton, CT 06340, USA

7. National Institute for Bioprocess Research and Training, 24 Foster's Ave, Belfield, Blackrock, Co., Dublin, A94 X099, Ireland

Abstract

A low-cost, modular, robust, and easily customisable continuous liquid–liquid phase separator has been developed that uses a tubular membrane and annular channels to allow high fluidic throughputs while maintaining rapid, surface wetting dominated, phase separation.

Funder

Science Foundation Ireland

European Regional Development Fund

Enterprise Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RE/D1RE00119A

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