Efficient fluorescent recognition of ATP/GTP by a water-soluble bisquinolinium pyridine-2,6-dicarboxamide compound. Crystal structures, spectroscopic studies and interaction mode with DNA

Author:

Viviano-Posadas Alejandro O.1ORCID,Romero-Mendoza Ulises1,Bazany-Rodríguez Iván J.1ORCID,Velázquez-Castillo Rocío V.1ORCID,Martínez-Otero Diego2ORCID,Bautista-Renedo Joanatan M.2,González-Rivas Nelly2ORCID,Galindo-Murillo Rodrigo3ORCID,Salomón-Flores María K.1ORCID,Dorazco-González Alejandro1ORCID

Affiliation:

1. Institute of Chemistry, National Autonomous University of Mexico, Circuito Exterior, Ciudad Universitaria, México, D.F., 04510, Mexico

2. Centro Conjunto de Investigación en Química Sustentable UAEM-UNAM, km 14.5 Carrera Toluca-Atlacomulco, Campus UAEMex “El Rosedal” San Cayetano-Toluca, Toluca de Lerdo 50200, Estado de México, Mexico

3. Department of Medicinal Chemistry, College of Pharmacy, University of Utah, 2000 East 30 South Skaggs 306, Salt Lake City 84112, Utah, USA

Abstract

A dicationic pyridine-2,6-dicarboxamide-based compound 1 bearing two N-alkylquinolinium units was synthesized, determined by single-crystal X-ray diffraction, and studied as a fluorescent receptor for nucleotides and inorganic phosphorylated anions in pure water.

Funder

Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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