A single pot organocatalytic diastereoselective synthesis of fluorescent ring fused 2-pyridone decalines via a domino Knoevenagel/Michael/hydro-lactamisation sequence-Reference-Cited by-同舟云学术

A single pot organocatalytic diastereoselective synthesis of fluorescent ring fused 2-pyridone decalines via a domino Knoevenagel/Michael/hydro-lactamisation sequence

Published:2021 Issue:18 Volume:8 Page:5032-5039
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Kamble Sumit B.¹²³^ORCID,Bhore Ranjeet K.¹,Tilve Santosh G.³^ORCID

Affiliation:

1. Department of Salt and Marine Chemicals, CSIR-Central Salt and Marine Chemicals Research Institute, Gijubhai Badekha Marg, Waghawadi road, Bhavnagar, Gujarat – 364002, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, Uttar Pradesh, India

3. School of Chemical Sciences, Goa University, Taleigao Plateau, Goa – 403206, India

Abstract

A highly efficient one-pot triple cascade approach is developed to synthesise fluorescent, fused, octahydro-2-pyridone decalines in good to excellent yields using l-proline/PhCOOH as an organocatalyst.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00582K

Reference41 articles.

1. Pyridone Alkaloids from a Marine-Derived Fungus, Stagonosporopsis cucurbitacearum, and Their Activities against Azole-Resistant Candida albicans

2. Bacterial Topoisomerase Inhibitors: Quinolone and Pyridone Antibacterial Agents

3. 4-Hydroxy-2-pyridone alkaloids: Structures and synthetic approaches

4. Topoisomerase I inhibitors: camptothecins and beyond

5. Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview

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