Theabrownin from Fu Brick tea ameliorates high-fat induced insulin resistance, hepatic steatosis, and inflammation in mice by altering the composition and metabolites of gut microbiota

Author:

Lu Zhongting1,Zheng Yan2,Zheng Juan34,Liang Qijian1,Zhen Qingcai1,Cui Mengjie1,Yang Haoru1,Wu Haotian1,Tian Cuixia1,Zhu Kangming1,Bian Chunyong1,Du Lei12ORCID,Wu Hao12ORCID,Guo Xin12ORCID

Affiliation:

1. Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China

2. Research Center of Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250013, China

3. Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

4. Hubei Provincial Clinical Research Center for Diabetes and Metabolic Disorders, Wuhan 430022, China

Abstract

The composition and metabolites of gut microbiota play important roles in improving insulin resistance, hepatic steatosis, and inflammation by theabrownin from Fu Brick tea.

Funder

Shandong University

Publisher

Royal Society of Chemistry (RSC)

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