Highly sensitive CD40L protein discrimination via label-free fiber sensing technologies

Author:

Hu Mingxuan1,Li Xuying2,Li Yansong3,Wang Ruiduo14ORCID,Kang Tongyuan1,Xu Fuxing5,Bai Jintao1,Jiang Man1,Zhu Yaomin3

Affiliation:

1. State Key Laboratory of Photon-Technology in Western China Energy, International Collaborative Center on Photoelectric Technology and Nano Functional Materials, School of Physics, Institute of Photonics & Photon Technology, Northwest University, Xi'an 710069, People's Republic of China

2. Department of Anesthesiology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou 570100, Hainan, China

3. Department of Anesthesiology & Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, The People's Republic of China

4. State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Science, Xi'an, 710119, China

5. Department of Anesthesiology, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan 030013, Shanxi, China

Abstract

A label-free and sensitive biosensor using surface modified etched fiber cascaded waveguides was developed to quantify the concentration of CD40L protein in human serum samples.

Funder

National Natural Science Foundation of China

Natural Science Basic Research Program of Shaanxi Province

Publisher

Royal Society of Chemistry (RSC)

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