1. Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan
2. Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan
3. Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan
4. Center of Applied Nanomedicine, National Cheng Kung University, Tainan 701, Taiwan