Aggregation-induced emission silence-mediated pathogen detection using a rapidly degradable nanographene-embedded polymersome

Author:

Cheng Chia-Yi1ORCID,Varghese Eldhose V.1,Wang Wen-Jyun1,Yao Chia-Yu1,Chen Chia-Hsiang12ORCID,Li Wei-Peng1234

Affiliation:

1. Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan

2. Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan

3. Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan

4. Center of Applied Nanomedicine, National Cheng Kung University, Tainan 701, Taiwan

Abstract

Enhancing the aggregation-induced emission (AIE) of nanographene by embedding it into the shell of bacteria-degradable polymersome was achieved, which enables an eye-visible AIE silence under the presence of bacteria for infected wound detection.

Funder

National Science and Technology Council

Publisher

Royal Society of Chemistry (RSC)

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