AuNCs–LHRHa nano-system for FL/CT dual-mode imaging and photothermal therapy of targeted prostate cancer

Author:

Wang Ze1,He Liang2,Che Songtian3,Xing Huiyuan1,Guan Lin1,Yang Zhe1,Li Xingchen1,Zvyagin Andrei V.45ORCID,Lin Quan1ORCID,Qu Wenrui6

Affiliation:

1. State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, P. R. China

2. Department of Urology, The First Hospital of Jilin University, Changchun, 130021, Jilin, China

3. Department of Ocular Fundus Disease, The Second Hospital of Jilin University, Changchun 130022, China

4. Australian Research Council Centre of Excellence for Nanoscale Biophotonics, Macquarie University, Sydney, NSW 2109, Australia

5. Institute of Biology and Biomedicine, Lobachevsky Nizhny Novgorod State University, 603105, Nizhny Novgorod, Russia

6. Department of Hand Surgery, The Second Hospital of Jilin University, Changchun 130000, P. R. China

Abstract

The AuNCs-LHRHa nano-system, which combines dual-mode imaging and targeted therapy, will provide a promising strategy for the integration of FL/CT diagnosis and PTT therapy for GnRH-R positive prostate cancer.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Jilin Province

Education Department of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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