Amine dehydrogenases: efficient biocatalysts for the reductive amination of carbonyl compounds

Author:

Knaus Tanja123ORCID,Böhmer Wesley123,Mutti Francesco G.123ORCID

Affiliation:

1. Van't Hoff Institute for Molecular Sciences (HIMS)

2. University of Amsterdam

3. The Netherlands

Abstract

Optimised dual-enzyme (AmDH–FDH) reductive amination of a broad range of carbonyl compounds affords enantiopure amines with a conversion of up to 99% using ammonia as an amine donor and formate as a reducing reagent.

Funder

European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference85 articles.

1. H. A. Wittcoff , B. G.Rueben and J. S.Plotkin, in Industrial Organic Chemicals, Wiley-Interscience, New York, 2nd edn, 2004

2. Chiral amine synthesis: Methods, Developments and Applications, ed. T. C. Nugent, Wiley-VCH, Weinheim, 2010

3. Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

4. S. K. Au , J.Groover, B. D.Feske and A. S.Bommarius, in Organic Synthesis Using Biocatalysis, Elsevier, 1st edn, 2015, pp. 187–212

5. Optisch aktive Amine durch Lipase-katalysierte Methoxyacetylierung

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