Discovery of selective, antimetastatic and anti-cancer stem cell metallohelicesviapost-assembly modification-Reference-Cited by-同舟云学术

Discovery of selective, antimetastatic and anti-cancer stem cell metallohelicesviapost-assembly modification

Published:2019 Issue:37 Volume:10 Page:8547-8557
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Song Hualong¹²³⁴^ORCID,Rogers Nicola J.¹²³⁴^ORCID,Allison Simon J.⁵⁶⁷⁴,Brabec Viktor⁸⁹¹⁰¹¹^ORCID,Bridgewater Hannah¹²²³⁴,Kostrhunova Hana⁸⁹¹⁰¹¹,Markova Lenka⁸⁹¹⁰¹¹,Phillips Roger M.⁵⁶⁷⁴,Pinder Emma C.⁵⁶⁷⁴,Shepherd Samantha L.⁵⁶⁷⁴,Young Lawrence S.¹²²³⁴,Zajac Juraj⁸⁹¹⁰¹¹,Scott Peter¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Warwick

3. Coventry CV4 7AL

4. UK

5. School of Applied Sciences

6. University of Huddersfield

7. Huddersfield

8. The Czech Academy of Sciences

9. Institute of Biophysics

10. CZ-61265 Brno

11. Czech Republic

12. Warwick Medical School

Abstract

A remarkable array of mechanistic and pharmacological behaviours is discoveredviaclick derivatisation of asymmetric, optically pure helicate-like compounds.

Funder

University of Warwick

China Scholarship Council

Czech Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC02651G

Reference82 articles.

1. Spontaneous assembly of double-stranded helicates from oligobipyridine ligands and copper(I) cations: structure of an inorganic double helix.