Exclusive formation of imino[4 + 4]cycloaddition products with biologically relevant amines: plausible candidates for acrolein biomarkers and biofunctional modulators-Reference-Cited by-同舟云学术

Exclusive formation of imino[4 + 4]cycloaddition products with biologically relevant amines: plausible candidates for acrolein biomarkers and biofunctional modulators

Published:2015 Issue:3 Volume:6 Page:431-436
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Tsutsui Ayumi¹²³⁴,Pradipta Ambara R.¹²³⁴,Saigitbatalova Elena⁵⁶⁷⁸⁹,Kurbangalieva Almira⁵⁶⁷⁸⁹,Tanaka Katsunori¹²³⁴⁵

Affiliation:

1. Biofunctional Synthetic Chemistry Laboratory

2. RIKEN

3. Wako-shi

4. Japan

5. Biofunctional Chemistry Laboratory

6. A. Butlerov Institute of Chemistry

7. Kazan Federal University

8. Kazan 420008

9. Russia

Abstract

We synthetically demonstrate that eight-membered heterocycles are the exclusive products of the reaction of acrolein with biologically relevant amines via an imino[4 + 4]cycloaddition.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C4MD00383G

Reference51 articles.

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