Facemask analyses for the non-invasive detection of chronic and acute P. aeruginosa lung infections using nanoparticle-based immunoassays

Author:

Delgado-Cano David1,Clemente Antonio123ORCID,Adrover-Jaume Cristina12,Vaquer Andreu12,López Meritxell456,Martínez Rocío46,Roig Isabel M.6,Iglesias Amanda45,Cosío Borja G.456,de la Rica Roberto13ORCID

Affiliation:

1. Multidisciplinary Sepsis Group, Hospital Universitario Son Espases, Health Research Institute of Balearic Islands (IdISBa), Palma de Mallorca, Spain

2. Department of Chemistry, University of the Balearic Islands, Palma de Mallorca, Spain

3. CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III Madrid, Spain

4. Inflamación, Reparación y Cáncer en Enfermedades Respiratorias (i-RESPIRE), Hospital Universitario Son Espases, Health Research Institute of Balearic Islands (IdISBa), Palma de Mallorca, Spain

5. CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain

6. Department of Respiratory Medicine, Hospital Universitario Son Espases, Palma de Mallorca, Spain

Abstract

We present a method for detecting respiratory infections caused by P. aeruginosa that involves analyzing facemasks worn by patients with a nanoparticle-based biosensor. The obtained colorimetric signals are related to the bacterial load in lungs.

Funder

Instituto de Salud Carlos III

Govern de les Illes Balears

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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