Revealing the effect of intramolecular interactions on DNA SERS detection: SERS capability for structural analysis

Author:

Bao Ying1,Zhang Xiaonong2,Xiang Xiaoxuan1,Zhang Yujing1,Zhao Bing1ORCID,Guo Xinhua13ORCID

Affiliation:

1. State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, P. R. China

2. Key Laboratory of Polymer Ecomaterials Jilin Biomedical Polymers Engineering Laboratory Changchun Institute of Applied Chemistry Chinese Academy of Sciences, Changchun 130022, P. R. China

3. Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, College of Life Science, Jilin University, Changchun 130012, P. R. China

Abstract

The GCGC-quadruplex, G-quadruplex and duplex are selected as models to study the effect of various hydrogen bonds and base stacking based on SERS band intensity, shift and appearance to verify the reliability of SERS detection.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Jilin Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

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