Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Design, synthesis and biological evaluation of β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity

Published:2019 Issue:7 Volume:10 Page:1109-1115
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Reßing Nina¹²³⁴⁵,Marquardt Viktoria⁶⁷⁸⁹¹⁰,Gertzen Christoph G. W.⁶⁷⁸⁹¹¹^ORCID,Schöler Andrea¹²³⁴⁵,Schramm Alexander¹²¹³¹⁴¹⁵⁹,Kurz Thomas⁶⁷⁸⁹,Gohlke Holger⁶⁷⁸⁹¹¹^ORCID,Aigner Achim¹⁶¹⁷³⁴¹⁸,Remke Marc¹⁰¹⁹²⁰⁸⁹,Hansen Finn K.¹²³⁴⁵^ORCID

Affiliation:

1. Pharmaceutical/Medicinal Chemistry

2. Institute of Pharmacy

3. Leipzig University

4. Medical Faculty

5. 04103 Leipzig

6. Institute for Pharmaceutical and Medicinal Chemistry

7. Heinrich Heine University Düsseldorf

8. 40225 Düsseldorf

9. Germany

10. Department of Pediatric Oncology

11. John von Neumann Institute for Computing (NIC)

12. Department of Pediatric Oncology and Hematology

13. University Children's Hospital Essen

14. University of Duisburg-Essen

15. 45122 Essen

16. Rudolf-Boehm-Institute for Pharmacology and Toxicology

17. Independent Division for Clinical Pharmacology

18. 04107 Leipzig

19. Hematology, and Clinical Immunology, Medical Faculty

20. Heinrich-Heine-University

Abstract

Novel β-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity were synthesized.

Funder

Deutsche Krebshilfe

Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C8MD00454D

Reference38 articles.

1. Epigenetics—An Epicenter of Gene Regulation: Histones and Histone-Modifying Enzymes

2. HDAC inhibitor-based therapies: Can we interpret the code?

3. Molecular Evolution of the Histone Deacetylase Family: Functional Implications of Phylogenetic Analysis

4. Histone Deacetylase 11 Is a Fatty-Acid Deacylase

5. Three proteins define a class of human histone deacetylases related to yeast Hda1p

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Perspectives and new aspects of histone deacetylase inhibitors in the therapy of CNS diseases;European Journal of Medicinal Chemistry;2023-10

2. Recent advances in anticancer peptoids;Bioorganic Chemistry;2023-10

3. Recent Progress in Histone Deacetylase (HDAC) 1 Inhibitors as Anticancer Agent;Current Cancer Drug Targets;2023-01

4. Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia;Journal of Medicinal Chemistry;2022-11-09

5. Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS^G12C Inhibitor;Journal of Medicinal Chemistry;2022-10-27

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3