PEGylated poly(diselenide-phosphate) nanogel as efficient self-delivery nanomedicine for cancer therapy

Author:

Li Chunting12345,Huang Wei12345,Zhou Linzhu12345,Huang Ping12345,Pang Yan12345,Zhu Xinyuan12345,Yan Deyue12345

Affiliation:

1. School of Chemistry and Chemical Engineering

2. State Key Laboratory of Metal Matrix Composites

3. Shanghai Jiao Tong University

4. Shanghai 200240

5. China

Abstract

A biocompatible, biodegradable and redox-responsive PEGylated poly(diselenide-phosphate) nanogel was synthesized. The nanogel can potently inhibit the proliferation of tumor cells. It is a potentially efficient and self-delivery nanomedicine for cancer therapy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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