Copper(i)-catalyzed [4 + 2] cycloaddition of aza-ortho-quinone methides with bicyclic alkenes-Reference-Cited by-同舟云学术

Copper(i)-catalyzed [4 + 2] cycloaddition of aza-ortho-quinone methides with bicyclic alkenes

Published:2021 Issue:15 Volume:19 Page:3379-3383
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lei Lu¹²³⁴⁵,Liang Yu-Feng¹²³⁴⁵,Liang Cui¹²³⁴⁵,Qin Jiang-Ke¹²³⁴⁵^ORCID,Pan Cheng-Xue¹²³⁴⁵^ORCID,Su Gui-Fa¹²³⁴⁵^ORCID,Mo Dong-Liang¹²³⁴⁵^ORCID

Affiliation:

1. State key laboratory for Chemistry and Molecular Engineering of Medicinal Resources

2. Ministry of Science and Technology of China

3. School of Chemistry and Pharmaceutical Sciences

4. Guangxi Normal University

5. Guilin

Abstract

An efficient copper(i)-catalyzed [4 + 2] cycloaddition of aza-ortho-quinone methides (ao-QMs) and bicyclic alkenes to prepare tetrahydroquinoline-fused bicycles bearing multiple stereocenters in good yields is reported.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00319D

Reference44 articles.

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4. Synthetic applications of type II intramolecular cycloadditions

5. Synthesis of Unsaturated N-Heterocycles by Cycloadditions of Aziridines and Alkynes

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