Enantioselective resolution of two model amino acids using inherently chiral oligomer films with uncorrelated molecular structures

Author:

Nulek Thitapond1,Arnaboldi Serena2ORCID,Salinas Gerardo3ORCID,Bonetti Giorgia4,Cirilli Roberto5,Benincori Tiziana4ORCID,Wattanakit Chularat1ORCID,Flood Adrian E.1ORCID,Kuhn Alexander13ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, School of Energy Science and Engineering, Vidyasirimedhi Institute of Science and Technology, 555 Moo 1, Payupnai, Wang Chan, Rayong 21210, Thailand

2. Dip. Di Chimica, Univ. degli Studi di Milano, Milan, Italy

3. Univ. Bordeaux, CNRS, Bordeaux INP, ISM UMR 5255, Pessac, France

4. Univ.degli Studi dell’Insubria, Dip. di Scienza e Alta Tecnologia, Via Valleggio 11, Como 22100, Italy

5. Istituto Superiore di Sanità, Centro Nazionale per il Controllo e la Valutazione dei Farmaci, Rome, Italy

Abstract

Chiral oligomers are proposed as templates for the chiral resolution of amino acids. High enantiomeric excess is achieved when they are employed as surfaces with electrochemically tunable hydrophilicity, despite their uncorrelated molecular structure.

Funder

Institut de chimie

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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