Rational design of 5-HT6R ligands using a bioisosteric strategy: synthesis, biological evaluation and molecular modelling
Author:
Affiliation:
1. Department of Medicinal Chemistry
2. Institute of Pharmacology Polish Academy of Sciences
3. 31-343 Kraków
4. Poland
5. Department of Crystal Chemistry and Crystal Physic
6. Jagiellonian University Faculty of Chemistry
7. 30-060 Kraków
Abstract
A bioisosteric strategy was successfully implemented with a screening protocol for new, potent 5-HT6R ligands.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA00054H
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