Hydride reduction of <i>o</i>-(fluorosilyl)benzodifluorides for subsequent C–F transformations-Reference-Cited by-同舟云学术

Hydride reduction of o-(fluorosilyl)benzodifluorides for subsequent C–F transformations

Published:2022 Issue:21 Volume:58 Page:3521-3524
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Idogawa Rika¹,Kobayashi Akihiro¹²,Kim Youngchan¹,Shimomori Ken¹,Hosoya Takamitsu¹^ORCID,Yoshida Suguru²^ORCID

Affiliation:

1. Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan

2. Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585, Japan

Abstract

An efficient method for sequential C–F transformations of o-(hydrosilyl)benzotrifluorides is disclosed. A key to the success is hydride reduction of o-(fluorosilyl)difluoromethylenes.

Funder

Japan Agency for Medical Research and Development

Naito Foundation

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D1CC06761C

Reference59 articles.

1. Fluorine in medicinal chemistry

2. Applications of Fluorine in Medicinal Chemistry

3. T.Hiyama and H.Yamamoto , Organofluorine Building Blocks , in Organofluorine Compounds , ed. H. Yamamoto , Springer , Berlin , 2000 , pp, 77–118

4. Single C−F Bond Activation of the CF 3 Group with a Lewis Acid: CF 3 ‐Cyclopropanes as Versatile 4,4‐Difluorohomoallylating Agents

5. Copper-Promoted Cross-Coupling Reactions for the Synthesis of Aryl(difluoromethyl)phosphonates Using Trimethylsilyl(difluoromethyl)phosphonate

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Advances in disilylation reactions to access cis/trans-1,2-disilylated and gem-disilylated alkenes;Chemical Communications;2024

2. Synthesis of Fluorenones and Xanthones through Intramolecular C–F Arylation;Bulletin of the Chemical Society of Japan;2023-03-24

3. C−F Transformations of Benzotrifluorides by the Activation of Ortho‐Hydrosilyl Group;The Chemical Record;2023-02-10

4. Selective Transformations of Aromatic Trifluoromethyl Groups through the Activation of Hydrosilanes;Journal of Synthetic Organic Chemistry, Japan;2022-10-01