Electrokinetic focusing of SARS-CoV-2 spike protein <i>via</i> ion concentration polarization in a paper-based lateral flow assay-Reference-Cited by-同舟云学术

Electrokinetic focusing of SARS-CoV-2 spike protein via ion concentration polarization in a paper-based lateral flow assay

Published:2024 Issue:1 Volume:16 Page:91-104
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Rahn Kira L.¹,Osman Sommer Y.¹,Pollak Quinlan G.¹,Anand Robbyn K.¹^ORCID

Affiliation:

1. Department of Chemistry, Iowa State University, 1605 Gilman Hall, 2415 Osborn Drive, Ames, IA 50011-1021, USA

Abstract

We report a method for electrokinetic focusing of a SARS-CoV-2 direclty over a test line comprising ACE receptors in a lateral flow assay. The method and design rules derived from this study are broadly applicable to a wide range of charged analytes.

Funder

Roy J. Carver Charitable Trust

Research Corporation for Scientific Advancement

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AY/D3AY00990D

Reference40 articles.

1. Ultrasensitive and Highly Specific Lateral Flow Assays for Point-of-Care Diagnosis

2. Performance evaluation of a lateral flow assay for nasopharyngeal antigen detection for SARS‐CoV‐2 diagnosis

3. Protein-based lateral flow assays for COVID-19 detection

4. Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19

5. Enhancing the analytical performance of paper lateral flow assays: From chemistry to engineering

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