Synthesis of fused indoline heterocycles via dearomatization of indoles with α-bromohydrazones: a systematic study on the substrates-Reference-Cited by-同舟云学术

Synthesis of fused indoline heterocycles via dearomatization of indoles with α-bromohydrazones: a systematic study on the substrates

Published:2017 Issue:7 Volume:15 Page:1651-1654
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Cao Wen-Bin¹²³⁴⁵,Xu Xiao-Ping¹²³⁴⁵,Ji Shun-Jun¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Organic Synthesis of Jiangsu Province

2. College of Chemistry

3. Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology

4. Soochow University

5. Suzhou

Abstract

An efficient metal-free dearomatization of indoles with α-bromohydrazones is reported. Various fused indoline heterocycles, which are potentially biologically active, were achieved in good yields (up to 94%) under mild conditions.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C6OB02362B

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