Facile one-pot synthesis of spirooxindole-pyrrolidine derivatives and their antimicrobial and acetylcholinesterase inhibitory activities
Author:
Affiliation:
1. College of Chemistry & Chemical Engineering
2. Yangzhou University
3. Yangzhou 225002
4. China
5. Pharmacy School
6. Huaihai Institute of Technology
7. Lianyungang 222005
8. College of Medicine
9. Yangzhou 225001
Abstract
A library of novel spirooxindole-pyrrolidine derivatives were facilely synthesized via 1,3-dipolar cycloaddition of azomethine ylide generated from sarcosine and paraformaldehyde with various 3-methyleneoxindolines.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ03813A
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