Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris

Author:

Heuer Christopher123ORCID,Jiang Xin1ORCID,Ron Gali1,Ternyak Orna4,Scheper Thomas2,Bahnemann Janina3ORCID,Segal Ester1ORCID

Affiliation:

1. Department of Biotechnology and Food Engineering, Technion – Israel Institute of Technology, Haifa, 3200003, Israel

2. Institute of Technical Chemistry, Leibniz University Hannover, Hannover 30167, Germany

3. Institute of Physics, University of Augsburg, Augsburg 86159, Germany

4. Micro- and Nanofabrication and Printing Unit, Technion – Israel Institute of Technology, Haifa, 3200003, Israel

Abstract

The application of a photonic silicon chip-based optical sensor system for expeditious and phenotypic antifungal susceptibility testing of Candida auris is presented.

Funder

Israel Science Foundation

Volkswagen Foundation

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference30 articles.

1. Emerging issues, challenges, and changing epidemiology of fungal disease outbreaks

2. Evolution of the human pathogenic lifestyle in fungi

3. WHO fungal priority pathogens list to guide research, development and public health action, https://www.who.int/publications/i/item/978924006024 , (accessed March 2023)

4. Candida auris’ potential link to climate change

5. The importance of antimicrobial resistance in medical mycology

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