Functionalized polyesters based on valerolactones and [12]aneN<sub>3</sub> as effective non-viral gene vectors in HepG2 cells-Reference-Cited by-同舟云学术

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Functionalized polyesters based on valerolactones and [12]aneN₃ as effective non-viral gene vectors in HepG2 cells

Published:2024 Issue:34 Volume:15 Page:3480-3491
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Zhang Xi¹,Xu De-Zhong¹,Zhang Zi-Han¹,Ren Zhi-Xuan¹,Wu Jia-Rao¹,Xu Yun-Jie¹,Lu Zhong-Lin¹^ORCID,Liu Rui¹,Liu Yang²^ORCID

Affiliation:

1. Key Laboratory of Radiopharmaceutics, Ministry of Education; College of Chemistry, Beijing Normal University, Beijing 100875, P. R. China

2. China National Institute for Food and Drug Control, Institute of Chemical Drug Control, HuaTuo Road 29, Beijing, 100050, China

Abstract

Block polyesters with BODIPY and [12]aneN3 moieties showed efficient cell-specific nucleic acid expression and anti-tumor gene therapy in vitro.

Funder

Natural Science Foundation of Beijing Municipality

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/PY/D4PY00610K

Reference59 articles.

1. Gene therapy returns to centre stage

2. Gene therapy comes of age

3. Gene therapy clinical trials, where do we go? An overview

4. The approved gene therapy drugs worldwide: from 1998 to 2019

5. Gene therapy for cancer

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